Indian company Lupin Ltd announced today that its subsidiary, Lupin Pharmaceutical Inc has received approval from the United States Food and Drug Administration (USFDA) to market a generic version of Lyrica (Pregabalin) capsules. The drug is used to treat pain associated with the effects on the nerves due to diabetes, herpes and fibromyalgia. LYRICA had annual U.S sales of approximately $1.8 billion for the twelve months ending March 2012 (IMS Health Sales Data).
This is not the first instance of an Indian company launching a generic drug in the US market.
Earlier Dr Reddy’s launched two generic drugs – a generic version of Roche’s anti-osteoporosis drug and another for acidity and heartburn – whereas Sun pharma launched a nasal spray for allergic rhinitis in the USA.
Hi Dr Pullen. It’s nice to have a doctor with an open mind as to meitdacions and their use, and one that takes the time to inform himself thoroughly. With that in mind, I feel I should tell you my experience with long-term use of Lyrica.Lyrica is very similar, as you say, to Neurontin, in that its absorption, mechanism, and elimination seem to fall along the same lines. Also, they both leave the body unchanged thus not metabolized, thus saving the patient’s liver!Lyrica, however, is somewhat insidious in that it virtually kills REM sleep, leaving one tired in the morning. I often find myself dreaming in the daytime, because I’m so deprived of this cathartic sleep cycle. I’m taking it for a nerve pain situation, but at this point, really, I am going to switch back to the Neurontin. Its half-life is far shorter, with which I’m more comfortable, and, true, it doesn’t cause loose bowels as does its counterpart, but the Neurontin allows one to have the critical REM sleep cycle, and for this reason, I urge great caution. Present your patients with the full picture of one vs the other, so they may make a wise choice. Often, they will choose the shorter-acting Neurontin because of the sleep effect.I know I might have stayed with it throughout my therapy, given this lesser-known but still very important side effect.Thanks
To,
The H.R Manager
myself Lkhande Umesh Ramchandra completed M. Pharm in Pharmaceutics in VIPER, Ale -412411(Pune).
so, sir i want to job in our organization.
Yours faithfully
LOKHANDE UMESH RAMCHANDRA