It is a genetic disease that is seen affecting the males in a family. The defective gene in the male causes a deficiency of clotting factor (which is required for normal clotting after bleeding). The disease can be caused by either deficiency of factor VIII (called Haemophilia A, occurs in 85% of cases) or factor IX (called Haemophilia B, occurs in 15% of cases).
Let’s understand the genetic inheritance by understanding various scenarios:
1. If the father has haemophilia but the mother does not, the sons will not have haemophilia. All of the daughters will become carriers of the gene.
2. If the mother is a ‘carrier’ of the defective haemophilia gene but the father is healthy, there is a 50:50 chance of a son suffering from haemophilia or the daughter being a carrier.
3. If the father has haemophilia and the mother is a carrier, the woman will suffer from haemophilia too. However, this is very rare.
Images courtesy: Haemophilia Federation India
First Published: Apr 17, 2012 at 10:50 AM
I thing are not for a person that is not eirepxenced with them esp if they are not puppies. They are stong headed and need good leadership and . THey can be aggressive toward other dogs esp if they have never been around them. But onthe other had. German shephards are great alert dogs, they can be good with kids and other dogs and a good family dog. It just depends on the person that owns them. The person that owns them have to be very dedicated to theri training and daily disaplin they can not have the run of the house!References : Has seen it both ways. Sister is a State Trooper K9 officer who own German Shepherds